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Why Symptoms Worsen at Night
Description
The sensation that symptoms worsen at night stems from a combination of the body's circadian rhythm and a lack of external distractions. During the night, there is a natural decline in cortisol levels—a hormone that suppresses inflammation—paired with an increase in immune system activity. This immune response releases pro-inflammatory substances that can trigger pain and fever. Furthermore, when lying quietly in bed, the brain becomes more focused on signals of pain and discomfort emanating from the body. Without the stimuli of the day to divert our attention, the intensity of the experience is significantly amplified.
Original title
למה תסמינים מחמירים בלילה
התחושה שהתסמינים מחמירים בשעות הלילה נובעת משילוב של המקצב הצירקדיני בגוף לבין היעדר הסחות דעת חיצוניות. במהלך הלילה חלה ירידה ברמות ההורמון קורטיזול, שמדכא דלקות, ועלייה בפעילות של מערכת החיסון המשחררת חומרים מעוררי דלקת הגורמים לכאב ולחום. בנוסף, כששוכבים בשקט במיטה, המוח מתמקד יותר באותות הכאב והאי-נוחות שמגיעים מהגוף, מה שמגביר את עוצמת החוויה.
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